Professor, Department of Cell Biology
Chanin Bldg., Room 416
718.430.2097
carl.schildkraut@einstein.yu.edu
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Demczuk, A., M. G. Gauthier, I.Veras, S. Kosiyatrakul, C. L. Schildkraut, M. Busslinger, J.Bechhoefer and P. Norio. 2012. Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment. PLoS Biology, PLoS Biol. 2012, e1001360. Epub 2012. PMID: 22807655.
Jeong, Y., M. Rossi, L. Cermak, A. Saraf, L. Florens, M.P. Washburn, P. Sung, C.L. Schildkraut, and M. Pagano. (2012). FBH1 mediates DNA double strand breakage and apoptosis in response to DNA replication stress. J Cell Biol., in press.
Drosopoulos, W. C., S. Kosiyatrakul, Z. Yan, S. G. Calderano, and C. L. Schildkraut. 2012. Human telomeres replicate using chromosome-specific, rather than universal, replication programs. J Cell Biol. 197: 253- 266. PMID 22508510.
Remeseiro, S., A. Cuadrado, M. Carretero, P. Martínez, W. C. Drosopoulos, M. Canamero, C. L. Schildkraut, M. A. Blasco, and A. Losada. 2012. Cohesin SA1 deficiency drives aneuploidy and tumorigenesis in mice due to impaired replication of telomeres. EMBO J 31: PMID: 22415365.
Borowiec JA, Schildkraut CL. Open sesame: activating dormant replication origins in the mouse immunoglobulin heavy chain (Igh) locus. Curr Opin Cell Biol. 2011 23:284-92. Epub (2011). PMID: 21571518.
Ott, E, Norio, P, Ritzi, M, Schildkraut, C.L., and A. Schepers. 2011. The dyad symmetry element of Epstein-Barr virus is a dominant but dispensable replication origin. PLoS One. e18609. Epub (2011) PMID: 21603652.
Verma, S.C., Lu, J., Cai, Q., Kosiyatrakul, S., McDowell, M., Schildkraut, C.L. and E. S. Robertson. Single molecule analysis of replicated DNA reveals the usage of multiple KSHV genome regions for latent replication. PLoS Pathogens (2011), e1002365. Epub 2011 Nov 3. PMID: 22072974
Schultz, S. S., Desbordes, S. C., Du, Z., Kosiyatrakul, S., Lipchina,, I., Studer, L. and Schildkraut, C. L. Single Molecule Analysis Reveals Changes in the DNA Replication Program for the POU5F1 Locus Upon hESC Differentiation. Mol. Cell. Biol., 18:4521-34. (2010). PMID: 20647538.
Sfeir, A., Kosiyatrakul, S. T., Hockemeyer, D., MacRae, S. L., Karlseder, J., Schildkraut, C.L., and De Lange, T., Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell, 138: 90-103. (2009). PMID: 19596237.
Desprat, R., Thierry-Mieg, D., Lailler, N., Schildkraut, C. L., Thierry-Mieg, J., and Bouhassira, E. E. Predictable Dynamic Program of Timing of DNA Replication in Human Cells. Genome Research. Genome Res. 19:2288-2299 (2009). PMID: 19767418.
Guan, Z., Hughes, C. M., Kosiyatrakul, S. T., Norio, P., Sen, R., Fiering, S., Allis, C. D Bouhassira, E. E., and Schildkraut, C. L. Decreased Replication Origin Activity in Temporal Transition Regions. Journal of Cell Biology. 187:623-35 (2009). PMID:19951913.
Norio, P., Kosiyatrakul, S.,Yang, Q., Guan, Z.,Brown, N., Thomas, S., Riblet, R., and Schildkraut, C.L. Progressive activation of DNA replication initiation in large domains of the immunoglobulin heavy chain locus during B cell development. Mol. Cell 20: 575 - 587(2005). PMID: 16307921.
Yang, Q., Riblet, R., Schildkraut, C.L. Sites that Direct Nuclear Compartmentalization are Near the 5' End of the Mouse Immunoglobulin Heavy Chain Locus. Mol. Cell. Biol. 25: 6021-6030 (2005). PMID: 15988016.
Norio P, Schildkraut C.L. Plasticity of DNA replication initiation in Epstein-Barr virus episomes. PLoS Biol 2: 816 - 833. (2004). PMID: 15208711.
Norio, P., Schildkraut, C.L. Visualization of DNA Replication on Individual Epstein-Barr Virus Episomes. Science 294: 2361-2364 (2001). PMID: 11743204.
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