Department of Cell Biology


Wenjun Guo, Ph.D -- Recent Publications



Associate Professor
Department of Cell Biology
Price Bldg., Room 122
(718) 678-1276

Research Interest
Recent Publications
Lab Members
Stem Cell Institute

1- Wang C, Christin JR, Oktay MH, Guo W. (2017) Lineage-biased stem cells maintain estrogen-receptor-positive and -negative mouse mammary luminal lineages. Cell Reports 18: 2825-2835.

2- Zhang Z, Christin JR, Wang C, Ge K, Oktay MH, Guo W. (2016) Mammary-stem-cell-based somatic mouse models reveal breast cancer drivers causing cell fate dysregulation. Cell Reports 16: 3146-3156.

3- Guo W. (2014) Breast cancer stem cells: regulatory networks, stem cell niches, and disease relevance. Stem Cells Translational Medicine 3:942-948.

4- Guo W, Keckesova Z, DonaherJ, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA. (2012) Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 148: 1015-1028.

5- Mani SA*, Guo W*, Liao MJ*, Eaton EN, Ayyanan A, Zhou A, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campell LL, Polyak K, Brisken C, Yang J, Weinberg RA. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-715. (*: equal contribution.)

6- Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG. (2006) Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell 126: 489-502.

Complete list of publications:

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