Marion Bessin Liver Research Center

Liver Cell Membrane Proteins: Expression and Function

Contact Us

Albert Einstein College of Medicine
625 Ullmann Building
1300 Morris Park Avenue
Bronx, NY 10461

Phone: 718.430.2098

 

Allan W. Wolkoff, MD
Professor (Medicine and Anatomy and Structural Biology)


The Liver Cell Membrane Proteins: Expression and Function Program Project focuses on functions and trafficking of specific liver cell membrane proteins. The studies (projects) comprising this program represent multidisciplinary approaches to several fundamental questions in liver pathobiology.

Projects 

All four Projects are concerned with interrelated areas of hepatocyte membrane biology and pathobiology, and each proposed project represents collaborative efforts between independent investigators.

  1. Project 1: Control of Vesicular Trafficking in the Hepatocyte
    Principal Investigator: Allan W. Wolkoff, M.D.  
  2. Project 2: Expression, Processing, and Function of Liver Gap Junctions
    Principal Investigator: David C. Spray, Ph.D.  
  3. Project 3: Genetic Analysis of Liver Membrane Protein Traffic
    Principal Investigator: Pamela Stanley, Ph.D.  
  4. Project 4: Interaction of Autophagic and Heterophagic Pathways in Liver Principal Investigator: Ana Maria Cuervo, M.D., Ph.D. 

Core Facilities 

  1. Core A: Administrative and Supporting Services Core
    Provides secretarial, bookkeeping, and common equipment functions. 
  2. Core B: Molecular Cytology Core
    Provides state-of-the-art microscopy and imaging services. 
  3. Core C: Proteomics Core
    Facilitates the substantial use of this technology by each of the four Projects. 

Faculty 

Allan W. Wolkoff, M.D., Program Director

Ruth H. Angeletti, Ph.D. 

Ana Maria Cuervo, M.D., Ph.D. 

John W. Murray, Ph.D. 

Phyllis M. Novikoff, Ph.D. 

David L. Silver, M.D., Ph.D. 

Erik L. Snapp, Ph.D. 

David C. Spray, Ph.D. 

Pamela Stanley, Ph.D. 

Duncan W. Wilson, Ph.D. 

Peter Satir, Ph.D. 

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