The Pilot and Feasibility Program, a vital component of the Liver Research Center, provides initial support for new investigators, allows established investigators to explore new directions, and enables the Center to attract scientists from other disciplines to liver research. During the past 10 years the Center has funded 31 feasibility studies.
The Marion Bessin Liver Research Center Core Grant has funds available to support several new Pilot and Feasibility Studies in the next fiscal year (June 1, 2013-May 31, 2014). These awards are given for one year and are renewable for a second year depending on suitable progress.
All academic full-time faculty are eligible to apply. Projects will be considered on any aspect of fundamental or applied research relating to basic liver function, pathophysiology or disease. The program is designed to support:
- New investigators with interest in liver-related research
- Established investigators in other disciplines who wish to begin research related to the liver
- Established investigators working in liver-related research who wish to begin a new project representing a major departure from their previous research
Second Year Pilot & Feasibility Studies (June 1, 2011-May 31, 2013)
Role of H1 Linker Histone in Liver Development and Gene Expression
P.I.: Arthur I. Skoultchi, Ph.D.
Mechanistic Study of Beneficial Effects of a Small Molecule on Lipid Metabolism
P.I.: Yuling Chi, Ph.D.
First Year Pilot & Feasibility Studies (June 1, 2012-May 31, 2013)
- Novel Approaches for Generating and Expanding Liver Progenitor Cells
P.I.: Wenjun Guo, Ph.D.
- Functional Assessment of Chaperone Mediated Autophagy in Drosophila
P.I.: Andreas Jenny, Ph.D.
Hypothalamic Autophagy in the Development of Hepatic Steatosis
P.I.: Rajat Singh, M.D., M.B., B.S.
Requests for Application
Applications should follow the format of a new NIH RO1 Grant, using NIH application forms (PHS 398) but reduced in length (Research Plan not to exceed 5-6 pages). Applications do not require institutional internal review or Dean's signature. Funds are available for 1-2 years with a maximum request of $25,000/year.
Interested individuals should please send a one-page letter of intent, including a brief description of the project and an NIH biosketch (including research support) by Friday, December 28, 2012. Due date for final submission will be announced later.
Applications will be reviewed by our Executive and Scientific Advisory Committees and notification of final status given by May 15, 2013.
Submit completed original and 7 copies to:
Dr. David A. Shafritz, Director
Ullmann Building, Room 603