Diseases That Could Affect Your Offspring
Individuals of Jewish descent (Ashkenazi,
Sephardi or Mizrahi) are likely to be carriers for at least one Jewish genetic
disease that could affect their offspring. Carriers of these types of diseases exhibit no
symptoms of the disease and usually do not have a family history of the
disease. A carrier will only know of his or her status after genetic testing,
or if he or she has a child who is affected with the disease. The latter can happen when two carriers of
the same disease have offspring together.
Were you tested with us in the past? If you are looking for your results, email: JewishGeneticHealth@Montefiore.org
To learn more about screening for the Jewish genetic diseases that can affect your offspring, visit PJGHtesting.com
Hereditary Breast & Ovarian Cancer
Breast cancer affects 1 in 8 women in the United States. Hereditary breast cancer accounts for approximately 5-10% of these breast cancers. Most cases of breast cancer are sporadic.
Ovarian cancer affects about 1 in 100 women. Hereditary ovarian cancer accounts for 10-15% of these cases. Most cases of ovarian cancer are sporadic.
A large proportion of hereditary breast and ovarian cancer can be linked to mutations in the BRCA genes.
Individuals of Ashkenazi Jewish descent have a significant risk to have a mutation in the BRCA gene and are therefore at a higher risk to develop breast, ovarian, and/or pancreatic cancer among other cancer types.
Visit BRCAcommunity.com to learn more.
Thanks in part to the generosity of the Foundation for Medical Evaluation & Early Detection, we are proud to offer subsidized testing for the three Ashkenazi Jewish BRCA founder mutations. Visit our BRCAcommunity Study page to learn more. We recently published the findings from our pilot year in a scientific journal. We are currently in the process of developing the next phase of the BRCAcommunity Study. For more information about the study or to express interest in participating, email us at firstname.lastname@example.org