Global Health Center

Marla Keller, M.D.

Contact Info

Dr. Marla Keller
Albert Einstein College of Medicine
1300 Morris Park Avenue
Mazer Building, Room 512
Bronx, NY 10461

718.430.3240
marla.keller@einstein.yu.edu 

 

 

Marla KellerAssociate Professor in the Department of Medicine (Division of Infectious Diseases) and Obstetrics and Gynecology and Women’s Health

Marla Keller, MD, Associate Professor in the Department of Medicine (Division of Infectious Diseases) and Obstetrics and Gynecology and Women’s Health, is a recipient of a pilot grant from the Global Health Center.

Research

Dr. Keller conducts investigator-initiated clinical trials to test the safety and efficacy of microbicides, drugs in development for vaginal or rectal application to prevent the transmission of human immunodeficiency virus and other sexually transmitted infections. Her studies also focus on defining the factors that contribute to innate mucosal immunity in the female genital tract.

Her pilot project was designed to determine if genital tract secretions collected from Rwandan women provide activity against bacteria and virus in the laboratory, if endogenous antimicrobial activity differs between HIV-infected and uninfected women, and if there is a difference in activity between women receiving hormonal contraception compared to women who are naturally cycling. Defining and characterizing this activity in different populations may lead to the identification of innate factors that could be exploited to augment host defense. Moreover, this activity may serve as a biomarker of a healthy genital tract mucosal environment and could be developed as a bioassay to evaluate the safety of microbicides in future clinical trials.

Click here to log in