Cores directed by outstanding investigators and operated by highly experienced technical staff provide CFAR investigators with access to the training, specialized scientific services and sophisticated instruments required for cutting-edge and novel research. These Cores are dynamic, adding new services and instruments in response to the needs of CFAR investigators identified during our strategic planning process. A short summary of each core is provided below with more detailed information provided by clicking on the Core name.
Clinical and Translational Investigation Core:
Provides investigators with a robust relational database of longitudinal data from almost 3,000 well-characterized HIV-infected patients to analyze outcomes, identify HIV patients with defined attributes and/or obtain specimens from a focused biorepository.
Biohazard Animal Core:
Supports the investigation of the in vivo pathogenesis of infection with HIV and HIV-associated pathogens by providing researchers with access to BSL3 animal facilities, novel humanized and transgenic mice, and facilities for imaging and behavioral analysis.
Provides CFAR investigators with a wide range of expertise and training required to perform detailed biostatistical analysis and power calculations for clinical, behavioral, epidemiological, genomic and basic science studies.
Flow Cytometry Core:
Provides access to sophisticated flow cytometry instruments to sort and analyze cells infected with HIV and other HIV-associated pathogens under appropriate biosafety containment and staff to perform phenotypic analysis of patient samples.
Immunology and Pathology Core:
Supports a wide range of assays to perform functional and anatomical analysis of immune responses and to analyze the histological appearance of cells and tissues from patients, animal and cultures infected with HIV and/or HIV-associated pathogens.
Provides infrastructure, molecular and functional assays to support clinical, translational and basic science research focused on investigating HIV infection, pathogenesis and therapy and to perform molecular and phenotypic analysis of HIV isolated from patients.
Supports the career development early stage investigators and the recruitment of non-HIV/AIDS investigators into HIV/AIDS research by providing extensive mentoring programs and pilot project research support.
Coordinates the CFAR strategic planning process and financial management of the scientific Cores and organizes and supports internal and external scientific seminars and symposia.