Albert Einstein Cancer Center

Molecular Genetics, Structure Function, Regulation Proton-Coupled Folate/Antifolate Transporter

   

idg  Dr. I. David Goldman
Departments of Molecular Pharmacology and Medicine, and the Albert Einstein Cancer Center
(718) 430-2594;  i.david.goldman@einstein.yu.edu
 
Key Words: Regulation,structure/function, physiological and pharmacological roles of a proton-coupled folate transporter and the genetics of hereditary folate malabsorption 

 

A postdoctoral position is available for studies on the structure-function, regulation and biological/pharmacological properties of the proton-coupled folate transporter (PCFT) cloned by this laboratory (Cell 127:917-28, 2006) and mutated in the autosomal recessive disorder, hereditary folate malabsorption. PCFT mediates intestinal folate absorption and transport of antifolate cancer chemotherapeutics into cancer cells within their acidic microenvironment. Candidates should have a strong background in molecular biology and/or physiology/electrophysiology/ homology modeling and a track-record of productivity during their doctoral training.  

 

 

 

 
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Message From the Director

I. David Goldman, M.D.

Since the start of the 20th century, scientists have sought ways of harnessing the immune system to attack cancer cells. The challenge has been enormous. The immune system is designed to destroy foreign ... 

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Albert Einstein Cancer Center
1300 Morris Park Avenue
Bronx, New York 10461
Telephone: 718.430.2302
aecc@einstein.yu.edu  

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