Nathan Shock Center of Excellence The NIA-supported Einstein Nathan Shock Center (E-NSC) represents a collection of nearly 80 internal and external faculty actively engaged in high-impact science and collaborations in the biology of aging, three innovative, state-of-the-art Research Resource Cores, and extensive opportunities for enrichment and training in aging research. The Nathan Shock Center is structured aroundfour research cores Proteostasis of Aging Protein quality control maintenance and homeostasis Director: Ana Maria Cuervo, M.D. Ph.D. Learn More Health Span Physiologic phenotyping through lifespan Director: Derek Huffman, Ph.D. Learn More Human Multi-omics Data Human high-throughput omics data sharing and technical advising Directors: Jan Vijg, Ph.D. and Nir Barzilai, M.D. Learn More Research Development Ensuring the future of Biology of Aging through mentoring, P&F funding, and education Directors: Rajat Singh, M.B.B.S. and Sofiya Milman, M.D. Learn More Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Publications See More A Comprehensive Management of Complicated Anterior Maxillary Crown Fracture in a 15-year-old Adolescent.A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.Shear stress turns on the primary cilium and lipophagy.Similar burden of pathogenic coding variants in exceptionally long-lived individuals and individuals without exceptional longevity.Remembering Beth Levine - the autophagy pioneer and woman extraordinaire.Geroscience in the Age of COVID-19.Plasma proteomic profile of frailty.FOXO3a acts to suppress DNA double-strand break-induced mutations.Genetics of extreme human longevity to guide drug discovery for healthy ageing.Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome.