Department of Cell Biology @ AECOM

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Top Story
	May 27, 2009 - Pamela Stanley, Ph.D. (professor of Cell B iology, Horace W. Goldsmith Professor) has been awarded the LaDonne H. Schulman Award for Excellence in Teaching. Congratulations to Dr. Pamela Stanley! <Full Story> - Comments from Dr. Arthur Skoultchi, Chairmen of Department of Cell Biology "At the Einstein graduation ceremonies this past week, Dr. Pamela Stanley was awarded the LaDonne H. Schulman Award for Excellence in Teaching. As we all know, Pamela is highly committed to the training of students and postdoctoral fellows, in her formal classroom teaching roles, in the her laboratory, and as the former Director of the Cell and Molecular Biology and Genetics Training Grant, as well as organizer of our WIP series and numerous Cell Biology retreats. Like Pamela, Dr. LaDonne Schulman, Professor of Developmental and Molecular Biology, was an outstanding teacher and a first-class researcher. Congratulations to Pamela on another very well deserved recognition of her contributions."

News
February 9, 2009 - Dr. Beibei Belinda Ding, a Postdoctoral Associate from Dr. B. Hilda Ye’s Lab will soon start at her new position as Research Assistant Professor of Anatomy & Cell Biology at University of Kansas Medical Center in Kansas City, Kansas. Let's wish her the best of luck and success in her future research career! Suzannah Williams, a Postdoc in Dr. Pamela Stanley’s lab has accepted a lecturer’s position in the Department of Physiology, Anatomy and Genetics at the University of Oxford, London. The best of luck, Suzannah! June 18, 2008 -- An Immunological Odyssey: A Symposium in Honor of. Stanley G. Nathenson, M.D.," was held on June 18 in Robbins Auditorium. The six renowned immunologists who spoke at the symposium included Peter C. Doherty, Ph.D., 1996 Nobel Laureate in Physiology or Medicine. <Full Story> Photo Gallery June 18th, 2007 -- the Department of Cell Biology hosted a one-day symposium honoring the scientific achievements of Dr. Jonathan R. Warner, the Joseph & Gertrud Buchler Chair in Translational Medicine in the Department of Cell Biology and Chairman of the department from 1983 to1998. After the opening remarks by Dean Allen Spiegel and Dr. Arthur Skoultchi, the current Chairman of Cell Biology, a number of distinguished guests reflected on Dr. Warner’s seminal discoveries in the field of ribosomal biogenesis as well as ongoing scientific pursuits in their own laboratories: Dr. James Darnell, Rockefeller University. "Four-plus decades of science and friendship"; Dr. Elaine Elion, Harvard University. "Tailoring mitogen-activated protein kinase cascades for differentiation and survival"; Dr. Alexander Rich, MIT. "The biology of proteins that bind to left-handed Z-DNA"; Dr. Stephen Udem, International AIDS Vaccine Initiative. "Vaccines: so much we now can do but too damned scared to do it!"; Dr. Joan Steitz, Yale University. "Regulatory RNPs: Altering outcomes in gene expression"; Dr. Ke Shuai, UCLA. "Protein SUMO ligases in the regulation of cytokine signaling and immunity"; Dr. Masayasu Nomura, University of California-Irvine School of Medicine. "Transcription of rRNA by RNA polymerase I is functionally coupled to rRNA processing and ribosome assembly". The scientific program concluded with a talk by Dr. Warner entitled “Ribosomes, RNA, and Friends.” Photo Gallery May, 2007 -- Michael Papetti, a Postdoc in Dr. Art Skoultchi’s lab and a good friend and colleague to many students and postdocs in this department, will move to his new position as an instructor in the Department of Medicine at Montefiore Hospital. The best of luck, Mike! December 15, 2006 - Dr. Yuhong Fan, an Instructor from Dr. Arthur Skoultchi's Lab will soon start at her new position as Assistant Professor of Molecular and Cell Biology at the Georgia Institute of Technology in Atlanta. Let's wish her GOOD LUCK and SUCCESS in her own lab!! December 18, 2006 - Dr. Margaret Kielian is named a member of the Editorial Board of Cell Host & Microbe, a new journal in the Cell Press family scheduled to be launching in March 2007.
New Ph. D
June 12, 2009 - KyeRyoung Lee of Dr. Winfrield Edelmann's Lab successfully defended her thesis. Our warmest congratulations to Dr. KyeRoung Lee and the Edelmann laboratory. February 4, 2009 - Qinrong Yan of Dr. Stanley Nathenson's Lab successfully defended his thesis. Our warmest congratulations to Dr. Qinrong Yan and the Nathenson laboratory. October 6, 2008 - Tsoni Peled and Fei Li Kuang of Dr. Matthew Scharff's Lab successfully defended their thesis. Our warmest congratulations to Dr. Tsoni Peled, Dr. Fei Li Kuang and the Scharff laboratory. April 22, 2008 - Lily Wu of Dr. Rick Kitsis' Lab successfully defended her Ph.D. thesis. Our warmest congratulations to Dr. Lily Wu and the Kitsis laboratory. September 20, 21, 2007 - Ja Young Kim and Zhao Wang of Dr. Philipp Scherer's Lab successfully defended their Ph.D. thesis. Our warmest congratulations to Dr. Ja Young Kim, Dr. Zhao Wang and the Scherer laboratory. September 17, 2007 - Yingfeng Deng of Dr. Robert Singer's Lab successfully defended her Ph.D. thesis. Our warmest congratulations to Dr. Yingfeng Deng and the Singer laboratory. November 6, 2006 - Erhu Cao of Dr. Stanley Nathenson's Lab successfully defended his Ph.D. thesis. Our warmest congratulations to Dr. Erhu Cao and the Nathenson laboratory. October 27, 2006 -- Lourdes Mendez of Dr. B. Hilda Ye's Lab successfully defended her Ph.D. thesis. Our warmest congratulations to Dr. Lourdes Mendez and the Ye laboratory!”
Awards
May 27, 2009 - Pamela Stanley, Ph.D. (professor of Cell B iology, Horace W. Goldsmith Professor) has been awarded the LaDonne H. Schulman Award for Excellence in Teaching. Congratulations to Dr. Pamela Stanley! <Full Story> July 22, 2008 -- Jennifer Aguilan, Research Associate in Dr. Pamela Stanley’s lab has been awarded a Postdoctoral Fellowship from the Muscular Dystrophy Association. December 18, 2007 -- Dr. Charles Query, Associate Professor of Department of Cell Biology, was awarded an "Irma T. Hirschl Career Scientist Award". November 5, 2007 -- Dr. Stanley G. Nathenson, Distinguished Professor of Microbiology & Immunology, and of Cell Biology, and Samuel H. Golding Professor of Microbiology, has been selected as the recipient of the second annual Marshall S. Horwitz, M.D. Faculty Prize for Research Excellence. The award ceremony and lecture will take place on Wednesday, January 16, 2008, at 4:00PM in the Robbins Auditorium. November 1, 2007 -- The Belfer Institute for Advanced Biomedical Studies recently held a competition for the fourth annual Outstanding Postdoctoral Research Scholar Prizes. Dr. Alexander Konev (laboratory of Dr. Dmitry Fyodorov) and Dr. Yong-Zhen Xu (laboratory of Dr. Charles Query) are among the six winners to receive this prize. They will present their award winning work at a ceremony on Monday, December 3, 2007 at 3:00 pm in Robbins Auditorium. October, 2007 -- Dr. Pamela Stanley was appointed last October as a permanent member of the Intercellular Communications and interactions (ICI) NIH study section. October 20, 2007 -- Dr. Kerri McIntosh, a Post-doc in Jon Warner's lab, was recently awarded a Postdoctoral Fellowship from NSERC, the Canadian equivalent of the NSF. Septemner 6, 2007 -- Laura Norwood, a postdoctoral associate in Arthur Skoultchi's lab was recently awarded an NIH fellowship. May 30, 2007 -- Dr. Michael Keogh, Assistant Professor of Department of Cell Biology, was awarded a "New York Academy of Medicine Speakers Fund for Biomedical Research award". April 18, 2007 -- Dr. Dmitry Fyodorov, Assistant Professor, received a "Scholar of the Sidney Kimmel Foundation for Cancer Research". April 11, 2007 -- Dean Allen Spiegel announced several endowed chairs for distinguished AECOM faculty members. Among these, Dr Pamela Stanley is the recipient of a chair established by the Horace Goldsmith Foundation. Dr. Eric Bouhassira will occupy another chair in Stem Cell Biology established by a generous gift from Ira and Ingeborg Rennert. Cheers to both Pamela and Eric! February 16, 2007 -- Erhu Cao, who recently defended his PhD thesis and is now a postdoctoral associate in Stanley Nathenson's lab, is one of the three recipients of 2007 Julius Marmur Research Awards. He will present his work at the 11th Annual Julius Marmur Symposium on Thursday, March 29, 2007 at 9:30 am. January 25, 2007 -- Dr. Rick Kitsis, Professor, Departments of Cell Biology and Medicine, is being chosen Chair of the Council on Basic Cardiovascular Sciences of the American Heart Association. January 22, 2007 -- Dr. Matthew Scharff, Distinguished Professor of Cell Biology and Medicine, has received the Faculty Mentoring Award for Research Excellence. Awards to be presented by Dean Allen Spiegel at Davidoff Day, Tuesday, January 30, 11:00AM, in the Riklis Auditorium concert hall. November 8, 2006 – Dr. Belinda Ding, a Postdoctoral associate in Dr. B. Hilda Ye’s lab, is the recipient of a one year fellowship grant from the Lauri Strauss Leukemia Foundation. October 16, 2006 -- Dr. Matthew Scharff, professor of cell biology and the Harry Eagle Professor of Cancer Research, has received the first annual Marshall S. Horwitz, M.D. Faculty Prize for Research Excellence. He will present his inaugural lecture on Wednesday, November 15, 2006, 4:00PM, in the Robbins Auditorium concert hall. February 16, 2006 -- Maofu Liao, a graduate student from Dr. Margret Kielian's lab, was selected for the 2006 Julius Marmur Research Award. Dr. Yuhong Fan, Dr. Ziqiang Li and Dr. Yuxun Wang received the second annual Outstanding Postdoctoral Research Scholar of the Belfer Institute for Advanced Biomedical Studies of year 2005.
New Faces
On July 17, 2008, Ms. Charissa Moctezuma joins Cell Biology Office as an Administrative Assistant. On July 7, 2008, Mr. Joseph Minuti joins Cell Biology Office as an Assistant Administrator. On March 3, 2008, Ms.Maria Chevere joins the Cell Biology Office as an Administrative Assistant effective. Maria comes to us from Berkley College. In February 2008, Dr. Ulrich Steidl joins the Department of Cell Biology as an assistant professor.
Top Notch Papers
Smith, D.J., Konarska, M.M., and Query, C.C. Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeast. Molecular Cell (2009) 34, 333–343. [PMID: 19450531] Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression. Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, Scharff MD. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16248-53. Epub 2008 Oct 14. A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion. Sánchez-San Martín C, Sosa H, Kielian M. Cell Host Microbe. 2008 Dec 11;4(6):600-8. Single-RNA counting reveals alternative modes of gene expression in yeast. Zenklusen D, Larson DR, Singer RH. Nat Struct Mol Biol. 2008 Dec;15(12):1263-71. Epub 2008 Nov 16. Qiu C, Olivier EN, Velho M, Bouhassira EE. Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells.Blood. 2008 Feb 15;111(4):2400-8. Epub 2007 Nov 16. Ge C, Stanley P. The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development.Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1539-44. Ding BB, Yu JJ, Yu RY, Mendez LM, Shaknovich R, Zhang Y, Cattoretti G, Ye BH. Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas. Blood.2008 Feb 1;111(3):1515-23. Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, Provenzano E, Ellis I, Figg N, Pinder S, Bennett MR, Caldas C, Kitsis RN. Regulation of p53 tetramerization and nuclear export by ARC. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20826-31. Xu, Y.-Z. and Query, C.C. (2007). Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assembly. Molecular Cell, 838-849. Yan Q, Malashkevich VN, Fedorov A, Fedorov E, Cao E, Lary JW, Cole JL, Nathenson SG, Almo SC. Structure of CD84 provides insight into SLAM family function. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10583-8. Ronai D, Iglesias-Ussel MD, Fan M, Li Z, Martin A, Scharff MD. Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation. J Exp Med. 2007 Jan 22;204(1):181-90. Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, Cuadrado M, Yang SM, Blasco MA, Skoultchi AI, Fernandez-Capetillo O. Global chromatin compaction limits the strength of the DNA damage response. J Cell Biol. 2007 Sep 24;178(7):1101-8. Konev AY, Tribus M, Park SY, Podhraski V, Lim CY, Emelyanov AV, Vershilova E, Pirrotta V, Kadonaga JT, Lusser A, Fyodorov DV. CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Science. 2007 Aug 24;317(5841):1087-90. Liu L, Query CC, Konarska MM. Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing. Nat Struct Mol Biol. 2007 Jun;14(6):519-26. Epub 2007 May 7. Cao E, Ramagopal UA, Fedorov A, Fedorov E, Yan Q, Lary JW, Cole JL, Nathenson SG, Almo SC. NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family. Immunity. 2006 Oct;25(4):559-70. Li Z, Zhao C, Iglesias-Ussel MD, Polonskaya Z, Zhuang M, Yang G, Luo Z, Edelmann W, Scharff MD. The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus. Immunity. 2006 Apr;24(4):393-403. Konarska MM, Vilardell J, Query CC. Repositioning of the reaction intermediate within the catalytic center of the spliceosome. Mol Cell. 2006 Feb 17;21(4):543-53.