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Selected Publications
2005/2006
Combs, T.P.,
Nagajyothi, Mukherjee, S., de Almeida C.J.G.,
Jelicks, L., Schubert, W., Lin, Y., Jayabalan,
D.S., Zhao, D., Braunstein, V.L.,
Landskroner-Eiger, S., Cordero, A., Factor, S.M.,
Weiss, L.M., Lisanti, M.P., Tanowitz, H.B. and P.
E. Scherer. 2005. The Adipocyte as an
Important Target Cell for Trypanosoma cruz
Infection. J. Biol. Chem., 280(25),
24085-24094.
Pajvani, U.B.,
Trujillo, M.E., Combs, T.P., Iyengar, P.,
Jelicks, L., Roth, K.A., Kitsis, R.N. and P. E.
Scherer. 2005. FAT Apoptosis Through Targeted
Activation of Caspase8 (FAT-ATTAC) a novel
mouse model of inducible and reversible lipoatrophy. Nat. Med,
11(7):797-803
Iyengar, P., Espina,
V., Berry, D., Williams, T., Jelicks, L.A., Lee,
H-K., Temple, K., Graves, R., Pollard, J.,
Chopra, N., Russell, R.G., Sasisekharan, R.,
Trock, B.J., Lippman, M., Calvert, V.S.,
Petricoin E.F., Liotta, L., Dadachova, E.,
Pestell, R.G., Lisanti, M.P., Bonaldo, P. and P.
E. Scherer. 2005. Adipocyte-Derived Collagen
VI Affects Early Mammary Tumor Progression in
vivo: A Novel Interaction in the Tumor / Stroma
Microenvironment. J. Clin. Inv.,
115(5):1163-1176
Nawrocki, A.R.,
Rajala, M.W., Tomas, E., Pajvani, U.B., Saha,
A.K., Trumbauer, M.E., Pang, Z., Chen, A.S.,
Ruderman, N.B., Chen, H., Rossetti, L. and P. E.
Scherer. 2005. Mice lacking adiponectin show
decreased hepatic insulin sensitivity and reduced
responsiveness to PPARgamma-agonists. J.
Biol. Chem., 281(5): 2654-2660
Nawrocki, A. and
Scherer, P.E.. 2005. The Adipocyte as a Drug
Discovery Target. 2005. Keynote Review.
Drug Discovery Today, 10 (18):
1219-1230
Trujillo, M.E.,
Pajvani, U.B. and P. E. Scherer. 2005. .
Apoptosis through Targeted Activation of
Caspase8. Novel mouse models of inducible and
reversible tissue ablation. . Cell Cycle,
4:9 e135-e139
Thematic Series in
Circulation Research: Adipocyte Signaling in the
Cardiovascular System
Guest Editor: Philipp E. Scherer
Berg, A.H. and P.E. Scherer. 2005.
Adipose Tissue, Inflammation and
Cardiovascular Disease Circ Res.,
96:939-949.
Trujillo, M.E. and P.
E. Scherer. 2005. Adiponectin: Journey from an
Adipocyte Secretory Protein to Biomarker of the
Metabolic Syndrome J. Internal Med.,
257(2):167-75
Bouskila, M.,
Pajvani, U.B. and P.E. Scherer. 2005.
Adiponectin ? A Relevant Player in PPARgamma
Agonist Mediated Improvements in Hepatic Insulin
Sensitivity? Int J Obes Relat Metab
Disord, 29 Suppl 1:S17-23
P. E. Scherer. 2006. Adipose Tissue: From Lipid Storage Compartment to
Endocrine Organ. Outstanding Scientific Achievement Award
Lecture. 2006. Diabetes, 55: 1537-1545
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Fisher, F.F.,
Trujillo, M.E., Hanif, W., Barnett, A.H.,
McTernan, P.G., Scherer, P.E. and S. Kumar. 2005.
Serum high molecular weight complex of
adiponectin correlates better with glucose tolerance
than total serum adiponectin in Indo-Asian
males. Diabetologia,
48(6):1084-1087.
Halperin, F.,
Beckman, J.A., Patti, M.E., Trujillo, M.E.,
Garvin, M., Creager, M.A., Scherer, P.E. and A.B.
Goldfine. 2005. The role of total and
high-molecular-weight complex of adiponectin in
vascular function in offspring whose parents both
had type 2 diabetes. Diabetologia, in
press.
Watson, E., Hahm, S.,
Mizuno, T.M., Windsor, J., Montgomery, C.,
Scherer, P.E., Mobbs, C.V. and S.R. Salton. 2005.
VGF Ablation Blocks the Development of
Hyperinsulinemia and Hyperglycemia in Several
Mouse Models of Obesity. Endocrinology,
in press
Jurgens, H., Haass,
W., Castaneda, T.R., Schurmann, A., Koebnick, C.,
Dombrowski, F., Otto, B., Nawrocki, A.R.,
Scherer, P.E., Spranger, J., Ristow, M., Joost,
H.G., Havel, P.J. and M.H. Tschop. 2005.
Consuming fructose-sweetened beverages
increases body adiposity in mice. Obes
Res., 13(7):1146-56.
Graveleau, C., Zaha,
V.G., Mohajer, A., Banerjee, R.R., Dudley-Rucker,
N., Steppan, C.M., Rajala, M.W., Scherer, P.E.,
Ahima, R.S., Lazar, M.A. and ED Abel. 2005.
Mouse and human resistin impair glucose
transport in primary mouse cardiomyocytes and
oligomerization is required for this biological
action. J Biol Chem., 280:
31679-31685.
Satoh, H., Nguyen,
M.T., Trujillo, M., Imamura, T., Usui, I.,
Scherer, P.E. and J.M. Olefsky. 2005.
Adenovirus-mediated adiponectin expression
augments skeletal muscle insulin sensitivity in
male Wistar rats. Diabetes, 2005,
54(5):1304-1313.
Vasseur, F.,
Helbecque, N., Lobbens, S., Vasseur-Delannoy, V.,
Dina, C., Clement, K., Boutin, P., Kadowaki, T.,
Scherer, P.E. and P. Froguel. 2005.
Hypoadiponectinaemia and high risk of type 2
diabetes are associated with adiponectin-encoding
(ACDC) gene promoter variants in morbid obesity:
evidence for a role of ACDC in diabesity.
Diabetologia, 48(5):892-9.
Capozza, F., Combs,
T.P., Cohen, A.W., Cho, Y.R., Park, S.Y.,
Schubert, W., Williams, T.M., Brasaemle, D.L.,
Jelicks, L.A., Scherer, P.E., Kim, J.K., and M.P.
Lisanti. 2005. Caveolin-3 (-/-) Knockout Mice
Show Increased Adiposity and Whole-Body Insulin
Resistance, with Ligand-Induced Insulin Receptor
Instability in Skeletal Muscle. Am J
Physiol Cell Physiol.
288(6):C1317-1331.
Bonuccelli, G.,
Sotgia, F., Frank, P.G., Williams, T.M., de
Almeida C.J., Tanowitz, H..B., Scherer, P.E.,
Hotchkiss, K.A., Terman, B.I., Rollman, B.,
Alileche, A., Brojatsch, J. and M.P. Lisanti.
2005. Anthrax Toxin Receptor (ATR/TEM8) is
Highly Expressed in Epithelial Cells Lining the
Toxin's Three Sites of Entry (Lung, Skin, and
Intestine). Am J Physiol Cell Physiol.
288(6):C1402-1410.
Bouatia-Naji, N., Meyre, D., Lobbens, S., Seron, K., Fumeron, F., Balkau,
B., Heude, B., Jouret, B., Scherer, P.E., Dina, C., Weill, J. and P.
Froguel. 2006. ACDC/Adiponectin Polymorphisms Are Associated With
Severe Childhood and Adult Obesity. Diabetes, 55(2):545-550.
Schattenberg, J.M., Singh, R., Wang, Y., Lefkowitch, J.H., Rigoli, R.M.,
Scherer, P.E. and M.J. Czaja. 2005. Jnk1 but not jnk2 promotes the
development of steatohepatitis in mice.
Hepatology, 22;43(1):163-172
Hertzel, A.V., Smith, L.A., Berg, A.H., Cline, G.W., Shulman, G.I.,
Scherer, P.E. and D.A. Bernlohr. 2005. Lipid Metabolism and Adipokine
Levels in Fatty Acid Binding Protein Null and Transgenic Mice. Am
J Physiol Endocrinol Metab. in press
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